糖化血红蛋白检测及临床应用

糖化血红蛋白检测及临床应用 ,?A???? (?????,?]?????e?????-?p??,?????]??314100) [???n??]u????+???d;???(?+?<??????;???d???? 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(?????????(???-?p??,????????831400) [???n??]u????S????????;??????;?I?????% [?r???0????]u?R0446.112u?u?u?[???n?)???,]u?Bu?u?u?[?????S??]u?10 08-8849(2007)07-0959-02 u?u????S????????(HbA1c)?J???1???2?????????????????? ?[??????,???????8?J?????7??u,?????6?.???0???????????? ???[?6?8,?%???????<????120d??,?????????????????? ??u(???5?????2,HbA1c?2???????????2????????,???o???? ?H????????1??2?M?[?????????I??,?6?2????????u,???4?J ?C????u,?J?C???%?????H?????H????,?J?????????<???hu,?? ?????????3?????????????)?)u( 1u??I?????? 15???e?????????????????? ???45??,?s8??,??3??;??????8??;???R6?M?[??3 ;??????????,????????5??u( 112u?????????u??????B??????(?.????????)???????????? ?????S?????)?e,???%???fDCA2000+???S????????/???? ?????????0????,DCA2000S??????,??????,?)????u(???? ???m?m2.5%??14%,?%???3?????????+???Su( 2u???u?u??? ???4?e1?b????HbA1c??>6.8%,??????>14%u(?I ???p?[?:?????????????I??????,?????3??????????,?[?0?% ???????????2,??????HbA1c??<6.8%,???????m6.2%u( 3u???u?u??? ???W?????e?m36%??68%,?????????4?????W ???????.u(??????%,???2???????????????W;?????? ??959???????r???p???[????ModernJournalofIntegratedTraditionalChin eseandWesternMedicine2007Mar,16(7) 112000200 11772070 a21101 HbA1c.. 74 11.5%,???2???<???4???%?,???+??????,?/???<???????+?? ??u,???]???Su,??????????????,???]???????????????r???? ?D?+??????u(????,?????????????4???????h?????),?5???? ???h???,???m???f,???????-??????2?bHbA1c????u(???? ?????????:??????????,?S?4???????h???,?.?f?????????% ?????????H?????????4,??????3?M?[????1?bHbA1cu( HbA1c???????d?????????h?????S,?????R?G?????]?) ???B??:d?HbA1c?????????4,?I???p?[??????,???????4?? ????11??????,?????????????r???????<?????l??u(d????B ?????4?????o:?%?-?????D????,?a???????????????????? ??,??HbA1c???W,???????????J???????B??u(d??????H?? ???????4?????????J?.?<??,??????????HbA1c,???????,?% 8%???R,?????????+????u,???????????????????<u(d??)?? ?I??????:?%????HbA1c???6??,?????????????????????< ??????????u(??HbA1c?m8%,?????????????????????m 711mmol/L,??????7.1mmol/L,???m???<???????h?.??,?? ???2???????????+?Hu,???Ju,???8???????/u,?????.??u,?D?+?? ???????]??,???3??????????u(??HbA1c?m8%,?????????B ??7.1mmol/L,?/?????W,???m???<???????h????,?????? ??,?????????.??u(?a???R??,?6??????HbA1c??????????, ?????????u?????d??????,?)??????u( ?p??,HbA1c???m???????????]u,????u,???????hu,?????3 ?W???]???????)?),?????)???I???????u?h?????????????? ??,???%???????????r?????%???????u???0????,?J???????? ?4?????????R????????Ht???)?)H=u(??3??6?M?[????1?b HbA1c,???????h??u,???:????????????,???????????????< ?????%???I??,?.???????4u( [?h?????<]u?2006-03-15 ?????S???4???4GGT/ALP?????????S?????B?? ?5?D?] (?????+???p??,?]?????]133000) [???n??]u??????S;GGT/ALP;?I???B?? [?r???0????]u?R0446.112u?u?u?[???n?)???,]u?Bu?u?u?[?????S??]u?10 08-8849(2007)07-0960-02 u?u??????5?4??????1060???????S???4?????43?-?s?%?? ??????(GGT)/???+??????(ALP)????,???%???????%?????S ?r???B??,???0???????????Ru( 1u??I?????? 111u????e????u????????m?????????4136??,?s92??,?? 44??,????(53.6??14.6)??;???????m?]1990???????????S ?7?????J?/???h?????)??,?I???????????????[?????????? ?????S???41060??,?s709??,??351??,????(54.1??11.9) ??;???r151?????????+?-??,280???????????+????,297?? ?????;???S??????u(?:??Child-pugh???0,??????A??217 ??,B??452??,C??391??u( 112u?????u????%???e??HITACHI7150???????<?S?0???? ????2?????4GGT??ALP??,????????????u( 113u????????1?0u?2???????????%t????,3???????????% ?????0??u( 2u???u?u??? ???4GGT/ALP?????????S???m1.03??0.84,???????m 0.46??0.31,2???????]?????+???((P<0.01)u(???4GGT/ ALP??????????A?????m1.18??0.87,B?????m1.08?? 0186,C?????m0.87??0.79,C????????????A??????B???? (P??<0.01)u(???4GGT/ALP?????????S???????+?-???? ?m0.87??0.72,?6?M???????+?-?????m1.05??0186,2???? ???]?????+???((<5)u(???4GGTL?????????S?? ???????+???????m36??85,?6?M?????????+???????m 1?8,???????]?????+???((<)u(???4GGT ALP?????????S?????;???S?????????m0.95??0.84,?6?M?? ???;???S???????m1.06??0.84,2?????????????+???(u( 3u???u?u??? ALP??GGT???a???????[?8?0??,?????????? [1-2] ,?J ?????????????<?)?),?%?????S???????????? [1,3] ,???d?4?? ???R???????.?6u(?e?5?????????2,?????S???4???4GGT/ ALP??????????????????u(???4GGT/ALP?????????????? ???R?????????6?8?8????,???]?????+???(u(???+?-???J?? ???S???D????????,?J???????D????????????u(?????S???? ???+?-???????4GGT/ALP?????????????M???????+?-?? ??,???2?????S???4???4GGT/ALP?????2??????,???2???? ???????R???]????????u(????,???4GGT/ALT?????????m ?d?????????????)?)u( ?????S???4?W?????????+???????;???S??????u(?????? ???????<ALPu,GGT?S???d????u,?????m???????????????< ALPu,GGT [1,4] u(?e?5?????m,?????S?????????+?????????4 GGT/ALP?????????????M?????????+??????,???2?????S ???4???4GGT/ALP?????2?????+?????]????????u(?????? ?????/?.?4??,?????2?????+?????????4GGT?????2??,?6 ???4ALP?????????.?2???????H?]??u(?W???????????+?? ?a???????<,???????????????????????+?S???d,?????????? ?????W?????+?S???d,???????????W???I???6?????????<?? ?? [5] u(?e?5?????m,?????S?????;???S?????????2?M?????; ???S???????????4GGTL???????????+???(,???2???? ?S???4???4GGTL?????2?;???S?????????2??????u(?? ??069???????r???p???[????ModernJournalofIntegratedTraditionalChineseandWesternMedicine2007Mar,16(7) P0.0/AP 1.0. 0910.12P0.01/ /AP /AP