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首页 Request for small animal imaging (uPET, uCT,…

Request for small animal imaging (uPET, uCT, uSPECT):用于小动物成像的要求(upet,UCT,uspect).doc

Request for small animal imagin…

郭若飞
2017-12-08 0人阅读 举报 0 0 暂无简介

简介:本文档为《Request for small animal imaging (uPET, uCT, uSPECT):用于小动物成像的要求(upet,UCT,uspect)doc》,可适用于高等教育领域

Requestforsmallanimalimaging(uPET,uCT,uSPECT):用于小动物成像的要求(upetUCTuspect)Requestforsmallanimalimaging(uPET,uCT,uSPECT)Investigator:Animalspecies:ModalitiesDepartment:Numberofanimals:TelEmailNoinjectionsanimalMaxvolume(ml)KostenplaatsRadiopharmaceutical(s):DECnoNoofanimalsscannedsimultaneously(uPET):Informationconcerningdate,time,scantypePreferreddate(s)ResolutionandFOV(uCT)Preferredtime()Preferredtime()CBMorDYN(uPET)CBMorDYN(uSPECT)Durationofscan(uPET)Durationofscan(uSPECT)Durationofscan(uCT)TotalscanningtimedayAdditionalinformationconcerningthescanBiotechnicalsupport(RequestingDepartmentCDPJWASijbesmaother)Animalheating(yesno)Anesthetic(s):Gatedacquisition(yesno)Gatingtype(ECGresp)ScanningtimecanonlybeassignedafteracopyoftheapprovedDECprotocolandacopyoftheapprovalletteroftheDEChavebeensentto:DrAvanWaarde,NucleaireGeneeskundeMoleculaireBeeldvorming,UMCG,Hanzeplein,GZGroningen,email:avanwaardengmbumcgnlWhentheprotocolinvolvesgeneticallymodifiedorganisms,acopyoftherelevantGGOpermissionshouldbesentaswellWithoutthesedocumentsyourrequestforscanningtimecannotbegrantedAdditionalinformationabouttheexperiment(ifnecessary)SignatureofinvestigatorDateElucidationoftheformThefollowingrulesapply:Foreachresearchprotocol(DECno)andscanningday,maximallyonehalfoftheworkingdaycanberequested,iehoursInexceptionalcases,longerscanningispossiblebutthereshouldbecompellingreasonsandpermissionshouldbegrantedbytheuPETteam(emailaddress:jwasijbesmangmbumcgnl)ScanswillonlybeenteredintotheplanningschemewhenallrelevantdocumentsareonfileattheDepartmentofNuclearMedicine(DECprotocol,DECletter,GGOpermit)Theinvestigatorshouldbecertainofthescanningdate“Perhapswewillneedthistime”isnobasisforplanningScanscannotbeplannedformorethanmonthsinadvance,unlessspecialpermissionhasbeengrantedbytheuPETteamWhenascanshouldbecanceled(egbecauseofuntimelydeathoftheanimals),theinvestigatorshouldimmediatelyinformJurgenSijbesma(jwasijbesmangmbumcgnl)orArenvanWaarde(avanwaardengmbumcgnl)Whenaninvestigatordoesnotshowupontheplanneddateortime,wemaydeletefurtherstudiesofthispersonfromourplanningschemeWhenaninvestigatordoesnotabidebytherulesandregulationsofourinstitution,heshemaybedeniedfurtherentrytothescanningfacilitiesRulesarelistedonthedooroftheuPETlabCleanupeverything,alwaysweartheappropriatelabcoatanddonotdamageanyhardorsoftwareONLYpeoplewhoarementionedontheDECprotocol(ie,investigatorshandlingexperimentalanimalsorinanyotherrespectinvolvedinthestudy)areallowedtoentertheuPETanduSPECTroomsNOvisitors,friends,orobserversareallowedtobepresentinanMLIIlab(Dutchlaw)Date:Theinvestigatorcanindicatepreferredscanningdate(s)Forvariousreasons(patientcaredemandingcyclotrontimeorradiochemicallabfacilities)itisnotalwayspossibletoscananimalsatthedesiredmomentIfproblemsarise,theinvestigatorwillbeconsultedandadateandtimewillbechosenwhichisconvenientforallpartiesinvolvedInthe“additionalinformation”rowoftherequestformtheinvestigatormayindicatearangeofdates(earliestandlatestdateatwhichthescanmaybeperformed)DECprotocols:CopiesofDECprotocol,DECapprovalandGGOpermissionshouldbemailedforthefollowingreasons:aTheDepartmentofNuclearMedicineisbylawobligedtoactinaccordancewiththeworkingprotocolwhichhasbeenapprovedbytheDECandtheMinistryofHealthbTheDepartmentofNuclearMedicineisanISOcertifiedorganizationthereforeallresearchprotocols,includingprotocolsforanimalexperiments,shouldbearchivedandkeptonfileduringaperiodofyearscIncompliancewiththeLawonWorkwithGeneticallyModifiedOrganisms,acopyoftherelevantGGOpermitsshouldbepresentinthelaboratoryroomwheresuchorganismsarebeinghandledRadiopharmaceuticals:ForinformationabouttracersavailableforuPETanduSPECTscanning,pleasecontact:PhilipElsinga(phelsingangmbumcgnl)orErikdeVries(efjdevriesngmbumcgnl)Numberofinjectionsperanimal:Severalprocesses(egbloodflowandglucosemetabolism,ormetabolismandreceptordensity)maybestudiedinasingleanimal,usingdifferenttracersAsingleanimalmayalsobescannedwiththesametraceratdifferenthoursoftheday,tomonitorchangesofasinglebiochemicalparameterasafunctionoftimeAnesthetics:Thefollowinganestheticsareavailableonaroutinebasis:()Isofluraneair()Ketaminemedetomidine()PentobarbitalIfanyotheranestheticisrequired,theinvestigatorshouldprovideitNumberofanimalsscannedsimultaneously:IntheuPETcamera,miceorratscanbescannedsimultaneouslywhichissometimesconvenientHowever,intheuSPECTanduCTscanners,onlyasingleanimalcanbeexaminedateachtime

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Request for small animal imaging (uPET, uCT, uSPECT):用于小动物成像的要求(upet,UCT,uspect)

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