GEE 推論性統計

2.???????? 101 304.12 ??? 156 464.82 1.???????? 109 463.95 2.???????? 43 421.97 ??? 208 485.51 ??? 233 274.63 ??? ????? GEE????? ??????????????????????????? ?????????????????????????????? ?????????????????????????????? ??????Generalized Estimating Equation?GEE??????? ?? GEE ????????????????????????? 86 ??????????????? Kolmogorov Smirnov ????? ??????????????????????????p ?? 0.003??? p ?? 0.200????????? p ?? 0.200???? ??????????p?? 0.072??? p?? 0.086?????? ??? p?? 0.018?????????????????p?? 0.029? ?? p?? 0.043????????? p?? 0.003???????? ?? p??? 0.05?????????????????????? ?? GEE?????? ?????? ? GEE ???????????????????????? ?????????????????????????????? ?????????????????????????????? ???????????????????????p?0.05??? 14????????????????????????????? ???????????????Z=2.53~4.71, p?.05??????? ?????????????????????????????? ???? ???????????????????????????? ??????????????? GEE ???????????? 87 ????????????????????????????? Y1=119.79?3.85X1?4.33X2?2.15X31?4.44X32?2.53X33?9.06X41? 10.31X42?9.04X51?17.57X52?Y1=???????????X1=?? ????X2=?????X31=????X32=????X33=????X41= ???X42=???X51=???*???X52=???*???? ???????????????????????????? ??????????????????????p?.0001~.01??? ?????????????????????????????? ?????????????????????????????? ????????????????? 9.04??????????? ????????????????????????????? ?????????????????????????????? ????????????????? 17.57 ?????????? ???? 119.58??? 147.70???? 2? ? 14???????????????????????????????? ???????? 95%???? ?? ??? ??? ??? ??? Z? Pr??Z? ?? 119.7860 2.2319 115.4116 124.1604 53.69 ?0.0001 1?????? ?=0??? ?=1? ?3.8475 2.6566 ?9.0534 1.3593 ?1.45 0.1475 2?????? 4.3255 2.1367 0.1346 8.5104 2.02 0.0431 88 ???=1? ??=2? 3????? ????? 2.1458 3.6726 ?5.0524 9.3440 0.58 0.5590 3????? ????? 4.4417 2.8019 ?1.0500 9.9335 1.59 0.1129 3????? ????? 2.5291 3.1243 ?3.5994 8.6527 0.81 0.4182 4????? 9.0556 1.9468 5.2399 12.8712 4.65 ?0.0001 4????? 10.3056 1.9844 6.4161 14.1950 5.19 ?0.0001 5???? ???? 9.0354 3.5717 2.0350 16.0357 2.53 0.0114 5???? ???? 17.5732 3.7271 10.2682 24.8783 4.71 ?0.0001 ?? ????Reference group??1???? 2????? 3???? 4????? 5??????? 89 測量時間 210 ? ? ? ? ? ? ? ? ? ? ? 150 140 130 120 110 組別 實驗組 對照組 ?????0???? 1???? 2???? ? ??????????? ????????? ?2 ????????? ???? 90 ? GEE????????????????????????? ?????????????????????????????? ?????????????????????????????? ???????????????p?0.05??? 15???????? ?????????????????????????????? ????Z=2.68~3.88, p?.05?????????????????? ????????????????????? ???????????????????????????? ??????????????? GEE ???????????? ??????????????????????????? Y2=24.91?2.24X1?3.22X2?1.98X31?2.43X32?1.91X33?0.36X41? 1.14X42?3.31X51?4.77X52?Y2=???????X2=??????X2= ?????X31=????X32=????X33=????X41=???X42= ???X51=???*???X52=???*???? ???????????????????????????? ??????????????????p?.0001~.005?????? ?????????????????????????????? ?????????????????????????????? ??????? 3.31????????????????????? 91 ?????????????????????????????? ?????????????????????????????? ? 4.77???????????? 25.42??? 31.33???? 3? ? 15?????????????????????????????? 95%???? ?? ??? ??? ??? ??? Z? Pr??Z? ?? 24.9147 1.0456 22.8654 26.9641 23.83 ?0.0001 1?????? ?=0??? ?=1? ?2.2374 1.2243 ?4.6370 0.1622 ?1.83 0.0676 2?????? ???=0? ??=1? 3.2221 0.7878 1.6781 4.7661 4.09 ?0.0001 3????? ????? 1.9800 1.1168 ?0.2090 4.1690 1.77 0.0763 3????? ????? 2.4265 1.3268 ?0.1740 5.0271 1.83 0.0674 3????? ????? 1.9128 1.0626 ?0.1698 3.9955 1.80 0.0718 4????? 0.3611 0.6726 ?0.9572 1.6794 0.54 0.5913 4????? 1.1389 0.7351 ?0.3019 2.5796 1.55 0.1213 5???? ???? 3.3056 1.2339 0.8872 5.7239 2.68 0.0074 5???? ???? 4.7702 1.2291 2.3612 7.1792 3.88 0.0001 ?? ????Reference group??1???? 2????? 3???? 4????? 5??????? 92 測量時間 210 ? ? ? ? ? ? ? ? ? 32 31 30 29 28 27 26 25 組別 實驗組 對照組 ?????0???? 1???? 2???? ? ??????????? ????????? ?3 ??????? ????????? ? GEE ???????????????????????? 93 ?????????????????????????????? ?????????????????p?0.05??? 16?????? ?????????????????????????????? ?????????Z=0.05~1.19, p?.05????????????? ??????????????????????? ???????????????????????????? ??????????????? GEE ???????????? ?????????????????????????????? Y3=54.05?2.93X1?4.11X2?2.66X31?4.10X ?4.19X33?7.44X41? 7.31X42?0.10X51?2.36X52?Y3=??????????X1=???? ??X2=?????X31=????X32=????X33=????X41=? ??X42=???X51=???*???X52=???*???? 32 ???????????????????????????? ????????????????????????? p ?.24~.73?????????????????????????? ?????????????????????????????? ???????????????????????? 0.10???? ?????????????????????????????? ?????????????????????????????? 94 ????????????????????? 2.36??????? ??????????????? 4? ? 16???????????????????????????????? ? 95%???? ?? ??? ??? ??? ??? Z? Pr??Z? ?? 54.0452 2.3781 49.3842 58.7062 22.73 ?0.0001 1??????? =0???? =1? 2.9252 2.2737 ?1.5312 7.3815 1.29 0.1983 2?????? ???=0?? ?=1? 4.1107 1.8354 0.5133 7.7080 2.24 0.0251 3????? ????? 2.6610 2.9026 ?3.0280 8.3500 0.92 0.3593 3????? ????? 4.1045 2.5945 ?0.9805 9.1895 1.58 0.1136 3????? ????? 4.1870 2.3304 ?0.3806 8.7545 1.80 0.0724 4????? 7.4444 1.4155 4.6700 10.2189 5.26 ?0.0001 4????? 7.3056 1.4713 4.4218 10.1893 4.97 ?0.0001 5???? ???? 0.1010 2.0753 ?3.9666 4.6186 0.05 0.9612 5???? ???? 2.3611 1.9813 ?1.5221 6.2444 1.19 0.2334 ?? ????Reference group??1???? 2????? 3???? 4????? 5??????? 95 測量時間 210 ? ? ? ? ? ? ? ? ? ? ? ? 72 70 68 66 64 62 60 58 組別 實驗組 對照組 ?????0???? 1???? 2???? ? ??????????? ????????? ?4 ?????????? 96