Writing Scientific Manuscripts
a guide for undergraduates
from the
Journal of Young Investigators
Peer-reviewed, undergraduate science journal.
Copyright 2005 Journal of Young Investigators.
www.jyi.org
This guide was written and produced by the Journal of Young
Investigators, Inc. It is distributed free as an education resource for
undergraduates, but may not be modified or reproduced without the
express written consent of the Journal of Young Investigators.
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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Table of Contents
Introduction ______________________________________ 4
Part I: Publication & Peer Review______________________ 6
Deciding to Publish _____________________________________ 6
Submitting Your Paper___________________________________ 6
After Submission _______________________________________ 6
Overview of Peer Review _________________________________ 7
Purpose of Peer Review __________________________________ 8
How It Works__________________________________________ 8
The Role of Editor ______________________________________ 9
Limitations and Issues___________________________________ 9
Part II: Writing a Scientific Manuscript ________________ 11
The Scientific Manuscript________________________________ 11
Structure of an Article_____________________________________________ 11
Writing Style ____________________________________________________ 13
Audience _______________________________________________________ 13
A Note on Scientific Misconduct _____________________________________ 14
Word Choice__________________________________________ 15
The Abstract__________________________________________ 17
What is an Abstract_______________________________________________ 17
Abstract Standards for Review ______________________________________ 19
Common Mistakes in an Abstract ____________________________________ 19
The Introduction ______________________________________ 20
What is an Introduction ___________________________________________ 20
Introduction Standards for Review ___________________________________ 22
Common Mistakes in an Introduction _________________________________ 23
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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The Methods & Materials Section__________________________ 24
What is a Methods & Materials Section________________________________ 24
Methods & Materials Section Review Standards _________________________ 26
Common Mistakes in a Methods & Materials Section _____________________ 26
The Results Section ____________________________________ 28
What is a Results Section? _________________________________________ 28
Results Section Review Standards ___________________________________ 28
Common Mistakes in a Results Section _______________________________ 29
The Discussion Section _________________________________ 30
What is a Discussion Section?_______________________________________ 30
Discussion Section Review Standards_________________________________ 31
Common Mistakes in a Discussion Section _____________________________ 32
Figures, Tables, Equations, and References__________________ 33
Figures & Tables _________________________________________________ 33
Captions _______________________________________________________ 34
Equations ______________________________________________________ 34
References _____________________________________________________ 35
Review Standards for These Elements ________________________________ 36
Common Mistakes in Figures & Tables ________________________________ 37
Common Mistakes in Captions ______________________________________ 37
Common Mistakes in Equations _____________________________________ 37
Common Mistakes in References ____________________________________ 37
Part III: Writing a Literature Review___________________ 39
What is a Literature Review? _____________________________ 39
Literature Review vs. Research Article ________________________________ 39
Writing a Literature Review: Preliminary Research ____________ 39
Writing a Literature Review: Analyzing the Literature__________ 41
Writing a Literature Review: Structure & Writing _____________ 42
Questions to Ask Yourself About Your Review __________________________ 43
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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Introduction
Welcome to JYI’s Guide to Reporting Scientific Research! This is a free guidebook,
written and distributed by the Journal of Young Investigators, an international
science research journal run entirely by undergraduates, for undergraduates.
This guide is designed as a resource for undergraduate science researchers who are
getting ready to write up their research for a journal. As an undergraduate, you
probably haven’t had the chance to write many professional papers. That will
change – quickly. Grad students and practicing scientists spend much of their time
writing scientific manuscripts, abstracts, and grant proposals.
This guide is laid out to give you an introduction to the publication process, peer
review, and writing scientific manuscripts. Peer review and publication are hot topics
in the scientific community. So much of the community lives under the constant
pressure of “Publish or Perish” that it must be a hot topic. Tenures are granted,
funding awarded, and professional reputations made based on how often – and how
well – a scientist publishes. As far as the scientific community is concerned, even
the most brilliant piece of research is useless unless reported – and reported well.
This guide is written for undergraduates, by undergraduates. Somewhere out there,
in that sea of opinions on publishing, are people who disagree with us on the
process, style, and content of research reports. We know that. This is not the be-all
and end-all bible on writing scientific manuscripts. It’s a guide for undergrads.
Listen to your advisor, read other manuscripts, and, above all, practice writing your
own. Come grad school, you’ll be glad you did.
What is JYI?
A quick digression, for those of you who were wondering . . .
The Journal of Young Investigators (JYI) is an international scientific research journal
run entirely by undergraduates, and publishing only undergraduate science research.
JYI is committed to filling a major gap in undergraduate science education: peer
review and publication.
Today, students have abundant opportunities to conduct scientific research;
however, they have precious few opportunities to communicate that research to their
peers in the scientific community. JYI and other undergraduate journals grant
students the chance to communicate their research, improve their technical and
scientific writing, and learn about this final and critical piece of the scientific process.
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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However, JYI goes one step further than other undergraduate journals. At JYI,
undergraduates direct, manage, and participate in every step of the publication
process. Undergraduates write the research papers, staff the editorial positions,
review the manuscripts, produce the general-audience articles, direct the
publications, formulate the business plans, write the grants, issue the press releases,
and direct every other part of the entire corporation, working with fellow students as
close as their home university and as far as the other side of the world. As a result,
JYI staff members learn—not only how to write and review scientific
manuscripts—but how a scientific journal works . . . and how to make one work!
Since undergraduates do not have all the scientific knowledge necessary to review
manuscripts, JYI employs professional scientists who work with JYI Associate Editors
to review Research manuscripts. These advisors play a crucial role in JYI, both by
improving the quality of reviews and in guiding JYI’s Associate Editors.
JYI is always hiring. Any undergraduate, from any university or country, may apply.
For information on what positions are currently available, please visit www.jyi.org.
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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Part I: Publication & Peer Review
When you are embroiled in publishing a paper, it can seem like the process is
complicated, difficult, and drawn-out. But the basics of any publication process are
the same: decide to publish, write, submit, wait, revise, publish.
Deciding to Publish
No scientist publishes the results of every single study she does. Some studies just
aren’t worth it. As an undergraduate, you will rely on your mentor to help you
decide when is the right time to publish. Usually, you’ll only publish when you have
something important to say: an interesting new result or conclusion to report to the
community.
Once you’ve decided to publish, you need to choose your forum. Some studies really
only warrant an abstract at a conference or a brief note to a journal. Some studies
warrant full-out reports. Again, as an undergraduate, you’ll work with your advisor
to decide what forum is best for your particular study.
If you decide to publish in a journal, the next question is: which journal?
Undergraduates rarely participate in writing reports for top-tier journals like Science,
or even field-specific top-tier journals like the Journal of Geophysical Review. Most
undergraduates publish in small, highly specialized journals. Again, you’ll work with
your advisor to decide which journal is the right one for your work.
(Shameless plug: all undergraduates, from any university or country, are welcome
to submit their research to the Journal of Young Investigators. At JYI, the
undergraduate is the lead author and works with the editors and reviewers through
every stage of the publication process. When publishing in most journals, the
undergraduate rarely gets a chance to participate in every level of publication. End of
plug.)
Submitting Your Paper
Once you’ve decided upon the journal, visit its website and thumb through old issues
to get a sense for its style and formatting. Usually, journals have special pages for
authors describing exactly what their submission policies are. Follow those
guidelines.
After Submission
Every journal deals with submission slightly differently, but they all follow the same
general format:
1. Author submits manuscript and figures to journal
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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2. Journal assigns the manuscript to an editor
3. Editor modifies to manuscript to remove any identifying information, then
sends it to several reviewers. Usually, the editor will send it to two or more
reviewers; however, some journals send their manuscripts to an entire review
board that reviews the papers together.
4. Some journals allow reviewers to accept or decline a review. Reviewers can
take months to decide if they will take on a review.
5. Reviewers review the paper. Usually, reviewers work alone, and they don’t
know who the other reviewers are. They can take a long time reviewing the
manuscripts, since they must be very thorough – and are usually very busy
themselves.
6. Reviewers return reviews, comments, and a recommendation to the editor.
Usually, the recommendation is something like: Accept, Accept With
Revisions, or Reject. The editor reads the reviews, considers the
recommendations (and the reasons behind those recommendations), and
decides whether or not to accept the paper.
7. If the paper is accepted, the editor will send the reviews and comments to the
author, usually asking for a revised edition of the paper.
8. The author revises the paper, and sends it back to the editor.
9. If the editor thinks the paper needs a second review, he/she may send it out
for another round. Otherwise, he/she sends it off to be published.
10. Publication. The whole process might have taken 6 months to a year!
Overview of Peer Review
Every year, hundreds of thousands of scientists conduct experiments, obtain results,
and draw conclusions. Most – if not all – of these conclusions contradict conclusions
drawn by other scientists. Which of these experiments are “good” science and which
are poor? How do we even begin to evaluate them all?
The scientific community relies on a process called peer review, or “refereeing”, to
decide which work is worthy of the community’s attention. Peer review is exactly
what it sounds like – researchers submit their work to a group of their peers, usually
well-respected and accomplished scientists who can be trusted to judge what is
“good” science and what is not. The group delivers a verdict, usually along with
substantial comments and recommendations.
Writing Scientific Manuscripts ! Journal of Young Investigators
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The scientific community uses peer review in just about every facet of its work.
Committees of scientists peer review grant proposals before allocating funding.
Groups of faculty and doctors review their colleague’s work when considering them
for tenure. And, most famously, scientists review each other’s research reports
before publication.
This guide will focus on peer review and publication.
Purpose of Peer Review
In the scientific community, peer review serves two major purposes:
• To filter what is published as “science”. The most obvious purpose of
peer review is to determine which papers report “good” science that a journal
can be proud to publish. No journal wants to publish unimportant, poorly
executed, flawed studies – and no scientist wants to read them.
• To provide researchers with perspective. Even the most gifted
researchers can’t catch all the flaws in a study. One function of peer review is
to allow a researcher’s colleagues to comment on the quality of her work
before it is published.
How It Works
An author writes a manuscript reporting his/her study (see Part II), and submits it to
a scientific journal. The manuscript is assigned to an editor to see it through the
peer review process, and the editor sends the manuscript (with names removed) to
several referees who will do the review. At most journals (including JYI), these
referees are called associate editors.
The referees review the manuscript, critiquing it and making comments, then return
their reviews to the editor. They also return recommendations for publication:
should our journal publish this paper? Usually, the recommendations are along the
lines of: 1) Accept unconditionally, 2) Accept after the author has made some
revisions, 3) Reject but ask the author to resubmit a revised version for additional
review, or 4) Reject outright.
The editor compiles the referees’ comments and sends them to the author,
anonymously.
One of the key features of this system is that it is anonymous. The referees do not
know who the author is and the author does not know who the referees are. The
referees do not act as a group, and no referee knows who the other referees will be
or what they will say. This design is to encourage candid feedback that is not
influenced by anything but the work itself.
Writing Scientific Manuscripts ! Journal of Young Investigators
Copyright 2005, Journal of Young Investigators, Inc.
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Some journals are changing this system slightly, and informing the author of the
referee’s identities. This is to establish some degree of accountability for the
referees. JYI does not reveal the identities of our reviewers.
The Role of Editor
The editor is the intermediary in the peer review process, but also the ultimate
judge. Referees make recommendations to the editor; however, the editor is under
no obligation to take their advice. When referees disagree on whether a manuscript
should be published, the editor can send the manuscript out for additional review, or
can decide then and there. The editor alone decides which manuscripts are
published and which are not.
The referee’s job, then, is not only to offer constructive criticism for the author, but
also to guide the editor to making the right decision about a manuscript. A referee
must substantiate his/her recommendations and provide enough reasoning and
evidence for the editor.
Limitations and Issues
“Editors and scientists portray peer review as a quasi-sacred process that helps to
make science our most objective truth teller. But we know that the system of peer
review is biased, unjust, unaccountable, incomplete, easily fixed, often insulting,
usually ignorant, occasionally foolish, and frequently wrong.”
-- Richard Horton, editor of The Lancet,
a prominent British peer-reviewed
science journal
The peer review system is far from perfect. Within the scientific community, it is
denounced more often than praised – but, as with democracy, it beat the alternative.
Some of the most common complaints about the peer review process are:
• It’s slow. Getting a paper peer reviewed can take months – sometimes even
years. It takes a long time to write the paper, to submit it, for the referees to
review it, for the editor to decide, for the author to make the revisions, for it
to be re-reviewed and re-revised . . .
• Conflicting views. Say an author sends out a paper that opposes a certain
theory, and the paper is reviewed by an advocate of that theory. It might be
very good science, and the referee might have very good objections, but it is
outside of the scope of the journal to decide which is right. The editor is then
in a difficult situation, trying to decide whether this is “good” science or not.
Writing Scientific Manuscripts ! Journal of Young Investigators
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This happens quite often, especially when editors bring their personal views of
science to bear on publication decisions.
• Personal views. Some people argue, perhaps legitimately, that the peer
review process is far too open to personal issues – jealousy, vendettas,
grudges, pet theories. Referees can be particularly critical of conclusions or
assumptions that contradict their own views of a subject. An editor must be
very careful in judging which opinions are based on objective evaluation and
which may be based on personal views unrelated to science.
• Fraud. Editors and referees assume that a paper is honestly written – that
is, that none of the results have been faked or evidence manipulated. When
scientific fraud has occurred, peer review often does not catch it. One of the
most famous cases of scientific fraud that went undetected by peer review
was the Schon scandel of 2001-2002. Jan Hendrik Schon was a German
physicist working at Bell Labs, who published 15 papers in Science and Nature
– both top-tier journals with rigorous peer review. The 15 papers reported
work he had done producing a transistor on the molecular scale – truly
revolutionary science - however, he had falsified results for all 15. The
papers were subsequently withdrawn after independent groups discovered the
fraud.
It’s important to remember that a paper accepted in peer review can still be poorly
written, poorly researched, and just plain wrong. Some of the most influential
manuscripts of the 20th century were never peer reviewed, including Watson and
Crick’s famous 1951 paper that announced the discovery
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